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Lucas Moreno Selected Research

Investigational Therapies (Experimental Therapy)

1/2022Access to early-phase clinical trials for children with relapsed and refractory neuroblastoma: A multicentre international study.
12/2020Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: A report from the Innovative Therapies for Children with Cancer (ITCC) consortium.
1/2020Phase II results from a phase I/II study to assess the safety and efficacy of weekly nab-paclitaxel in paediatric patients with recurrent or refractory solid tumours: A collaboration with the European Innovative Therapies for Children with Cancer Network.
1/2020Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.
12/2019Access to Clinical Trials for Adolescents and Young Adults With Cancer: A Meta-Research Analysis.
3/2018Outcome of children and adolescents with central nervous system tumors in phase I trials.
1/2018Phase I results of a phase I/II study of weekly nab-paclitaxel in paediatric patients with recurrent/refractory solid tumours: A collaboration with innovative therapies for children with cancer.
11/2017Revisiting the definition of dose-limiting toxicities in paediatric oncology phase I clinical trials: An analysis from the Innovative Therapies for Children with Cancer Consortium.
9/2017[Early clinical trials in paediatric oncology in Spain: a nationwide perspective].
8/2017Early phase clinical trials of anticancer agents in children and adolescents - an ITCC perspective.
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Lucas Moreno Research Topics

Disease

34Neoplasms (Cancer)
01/2022 - 01/2011
23Neuroblastoma
01/2022 - 01/2011
5Glioma (Gliomas)
01/2017 - 08/2010
3Rhabdomyosarcoma
12/2021 - 01/2020
3Ependymoma
07/2020 - 07/2010
2Sarcoma (Soft Tissue Sarcoma)
11/2021 - 01/2014
2Cytokine Release Syndrome
08/2020 - 08/2020
1Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
12/2021
1Neoplasm Metastasis (Metastasis)
01/2021
1Disease Progression
01/2021
1COVID-19
12/2020
1B-Cell Lymphoma (Lymphoma, B Cell)
07/2020
1Ewing Sarcoma (Sarcoma, Ewing)
01/2020
1Hemorrhage
01/2019
1Breast Neoplasms (Breast Cancer)
01/2018
1Leukemia
11/2016
1Thrombocytopenia (Thrombopenia)
01/2015
1Anemia
01/2015
1Neutropenia
01/2015
1Long Term Adverse Effects
07/2013
1Familial ependymoma
01/2013
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2012
1Hyperbilirubinemia
01/2012
1Respiratory Acidosis
01/2011
1Medulloblastoma
01/2011
1Asphyxia (Suffocation)
01/2011

Drug/Important Bio-Agent (IBA)

14Pharmaceutical PreparationsIBA
01/2022 - 01/2011
7Biomarkers (Surrogate Marker)IBA
01/2021 - 04/2016
3Biological ProductsIBA
01/2019 - 01/2013
2Proteins (Proteins, Gene)FDA Link
08/2021 - 04/2016
2Biological FactorsIBA
01/2021 - 10/2016
2tocilizumab (atlizumab)FDA Link
08/2020 - 08/2020
2Aurora Kinase AIBA
01/2020 - 01/2015
2130-nm albumin-bound paclitaxelIBA
01/2020 - 01/2018
2Antineoplastic Agents (Antineoplastics)IBA
11/2017 - 01/2011
2Aurora KinasesIBA
01/2017 - 01/2015
2Temozolomide (Temodar)FDA LinkGeneric
01/2017 - 11/2011
1RNA (Ribonucleic Acid)IBA
01/2022
1ceritinibIBA
12/2021
1Anaplastic Lymphoma KinaseIBA
12/2021
1CateninsIBA
11/2021
1WAY-262611IBA
11/2021
1Messenger RNA (mRNA)IBA
09/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2021
1Histone Deacetylase InhibitorsIBA
07/2020
1NucleotidesIBA
07/2020
1Chimeric Antigen ReceptorsIBA
07/2020
1MLN 8237IBA
01/2020
1vistusertibIBA
01/2020
1ABTL0812IBA
01/2020
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2019
1cediranib (AZD2171)IBA
01/2019
1Topotecan (Hycamtin)FDA LinkGeneric
01/2017
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2017
1Mechanistic Target of Rapamycin Complex 1IBA
01/2017
1Checkpoint Kinase 1IBA
01/2017
1Vincristine (Oncovin)FDA LinkGeneric
01/2017
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2017
1N-Myc Proto-Oncogene ProteinIBA
04/2016
1Oncogene Proteins (Oncogene Protein)IBA
04/2016
1dipinacoline glutamateIBA
01/2016
11- cyclopropyl- 3- (3- (5- morpholin- 4- ylmethyl- 1H- benzoimidazol- 2- yl)- 1H- pyrazol- 4- yl)ureaIBA
01/2015
1ImidazolinesIBA
01/2014
1Melphalan (Alkeran)FDA LinkGeneric
07/2013
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2013
1EndoglinIBA
01/2013
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2012
1Alanine Transaminase (SGPT)IBA
01/2012
1Clofarabine (Clolar)FDA Link
01/2012
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2012
1Sodium Bicarbonate (Baking Soda)FDA LinkGeneric
01/2011

Therapy/Procedure

25Therapeutics
01/2022 - 01/2011
13Investigational Therapies (Experimental Therapy)
01/2022 - 01/2015
5Immunotherapy
01/2022 - 01/2013
3Combined Modality Therapy
01/2022 - 07/2010
3Precision Medicine
01/2020 - 01/2019
3Drug Therapy (Chemotherapy)
01/2019 - 08/2010
3Induction Chemotherapy
01/2019 - 07/2013
1Injections
01/2020
1Oral Administration
01/2020
1Biological Therapy
01/2015